Pediatric oncology research in low income countries: ethical concepts and challenges.

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TitlePediatric oncology research in low income countries: ethical concepts and challenges.
Publication TypeJournal Article
Year of Publication2012
AuthorsDenburg, AE, Joffe, S, Gupta, S, Howard, SC, Ribeiro, RC, Antillon, FA, Vasquez, R, Sung, L
JournalPediatr Blood Cancer
Volume58
Issue4
Pagination492-7
Date Published2012 Apr
ISSN1545-5017
KeywordsBioethics, Biomedical Research, Child, Child, Preschool, Developing Countries, Female, Humans, Male, Medical Oncology
Abstract

Uneven strides in research and care have led to discrepancies in childhood cancer outcomes between high and low income countries (LICs). Collaborative research may help improve outcomes in LICs by generating knowledge for local scientific communities, augmenting knowledge translation, and fostering context-specific evaluation of treatment protocols. However, the risks of such research have received little attention. This paper investigates the relationship between pediatric oncology research in LICs and four core issues in the ethics literature: standard of care, trial benefits, ethics review, and informed consent. Our aims are to highlight the importance of this field and the need for further inquiry.

DOI10.1002/pbc.23419
Alternate JournalPediatr Blood Cancer
PubMed ID22147674